Application

Research CategoryNeuroscience

Anti-Myelin Protein P0 Antibody is a highly specific rabbit polyclonal antibody, that targets Myelin Protein & has been tested in western blotting & IHC (Paraffin).

Research Sub CategoryDevelopmental Neuroscience

Immunohistochemistry Analysis: A 1:2,000 dilution of this antibody detected Myelin protein P0 in rat spinal cord sections.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Myelin protein P0 is also called Myelin peripheral protein (MPP) and Myelin protein zero (MPZ). Myelin protein P0 is found only in peripheral nervous system and is involved in the creation of an extracellular membrane face which guides the wrapping process that eventually leads to the compaction of adjacent lamellae. Myelin protein P0 is related to several disease states including Charcot-Marie-Tooth disease 1B (CMT1B), Charcot-Marie-Tooth disease 2I (CMT2I), Charcot-Marie-Tooth disease 2J (CMT2J), Adie pupil (ADIEP), Charcot-Marie-Tooth disease, dominant, intermediate type, D (CMTDID), Dejerine-Sottas syndrome (DSS), Congenital hypomyelination neuropathy (CHN), and Roussy-Levy syndrome (ROULS).

Immunogen

KLH-conjugated linear peptide corresponding to the extracellular domain of human Myelin protein P0.

Physical form

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Quality

Evaluated by Western Blotting in rat spinal cord tissue lysate.

Western Blotting Analysis: A 1:5,000 dilution of this antibody detected Myelin protein P0 in 10 µg of rat spinal cord tissue lysate.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Target description

~30 kDa observed